Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease

Sosuga virus was firstly reported as a causative agent for human febrile illness who is a field worker in South Sudan and Uganda in 2012. The Sosuga virus was detected from Egyptian rousette bat in Uganda. The intranasal and intraperitoneal infection of Sosuga virus to Syrian hamsters resulted in viral replication in blood and tissues including liver, spleen, kidney and lung. The Syrian hamsters showed susceptibility to Sosuga virus in the absence of clinical signs and significant histopathological findings in tissues.