Transmission dynamics and vaccination strategies for Crimean-Congo hemorrhagic fever virus in Afghanistan: A modeling study

Crimean-Congo hemorrhagic fever virus (CCHFV) is endemic in an area of Afghanistan, Herat. Using the real world data of CCHFV infection in human and livestock, a mathematical modeling study to elucidate the transmission pattern of CCHFV and the  efficiency of vaccination has been performed. The increasing cases of CCHF was shown to be depend on the surveillance capacity, but not on the indeed increasing cases. Vaccination was found to be effective in case for humans, not for animals. Moreover, it was clear that vaccination is more effective in a high-risk group such as farmers, because CCHFV is transmitted to human from livestock via tick biting.