Monday, May 7, 2012
We know pathogens more than interferons
Our cells have a strategy to battle against
invading pathogens. The most famous one is the interferon. Cells secrete interferons
when they sense the invasion of pathogens. Neighboring cells receive signals by
the interferons. These cells synthesize several interferon-induced factors. For
example, an enzyme that cleaves the nucleic acids of pathogens, a factor that
inhibits the invasion of pathogens into the surface of cells, and a factor that
lets the host cellular activity stop, which causes the inhibition of growth of
pathogens. Although there are many interferon-induced factors, the detailed
characteristics of individual factors remain unclear. In contrast, the
pathogens have a strategy to disturb the synthesis and function of the
interferons. The study of pathogen’s disturbance is being improved more than
that of interferon-induced factors. It is likely that to find the weak points
of enemies is effective for the development of drugs.
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