Sunday, April 18, 2021

SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization

SARS-CoV-2 can be transmitted from human to mink, which was observed in Europe and US. A point mutation Y453F in SARS-CoV-2 spike protein was found from mink. This mutation is involved in the reduction of neutralizing efficiency of therapeutic antibody and sera from COVID-19 patients against SARS-CoV-2 infection.

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