The neutralizing activity of totally 20 human sera derived from individuals who received BNT162b2 mRNA vaccine drawn 2 or 4 weeks after two doses of vaccination against engineered SARS-CoV-2 with Wuhan type background possessing a mutant spike gene from 3 India variants (B.1.167.1, B.1.167.2 and B.1.168) or 1 Nigeria variant (B.1.525) was examined. Although the neutralizing activity against B.1.167.1 was slightly lower than that against Wuhan type, all these viruses were enoughly neutralized by these sera, suggesting that BNT162b2 is effective for these India and Nigeria variants.
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